T Nagatsu Selected Research

Dopa-responsive Dystonia

12/2000	[Molecular mechanisms of neurotransmission].
9/2000	Molecular mechanisms of hereditary progressive dystonia with marked diurnal fluctuation, Segawa's disease.
3/2000	Normal values and age-dependent changes in GTP cyclohydrolase I activity in stimulated mononuclear blood cells measured by high-performance liquid chromatography.

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T Nagatsu Research Topics

Disease

11	Parkinson Disease (Parkinson's Disease) 09/2012 - 01/2000
5	Parkinsonian Disorders (Parkinsonism) 01/2006 - 01/2000
3	Dopa-responsive Dystonia 12/2000 - 03/2000
2	Neuroblastoma 06/2007 - 09/2000
2	Pheochromocytoma 05/2005 - 07/2002
2	Movement Disorders (Movement Disorder) 01/2005 - 09/2000
1	Septic Shock (Toxic Shock Syndrome) 06/2007
1	Endotoxemia 06/2007
1	Lewy Body Disease (Lewy Body Dementia) 01/2006
1	Neoplasms (Cancer) 07/2005
1	Tremor (Tremors) 05/2002
1	Muscle Rigidity 05/2002
1	Aberrant Crypt Foci 12/2001
1	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 10/2001
1	Dystonia (Limb Dystonia) 12/2000
1	B BH4-Deficient Hyperphenylalaninemia 12/2000
1	Neurodegenerative Diseases (Neurodegenerative Disease) 09/2000
1	Breast Neoplasms (Breast Cancer) 05/2000
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2000
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2000

Drug/Important Bio-Agent (IBA)

6	Dopamine (Intropin)FDA LinkGeneric 01/2005 - 01/2000
5	GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA 06/2007 - 03/2000
5	CytokinesIBA 06/2007 - 01/2000
4	EnzymesIBA 06/2007 - 09/2000
4	sapropterin (tetrahydrobiopterin)FDA Link 06/2007 - 03/2000
4	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 06/2007 - 07/2000
3	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2006 - 01/2000
3	Protein Isoforms (Isoforms)IBA 10/2001 - 05/2000
2	Selegiline (E250)FDA LinkGeneric 09/2012 - 07/2011
2	Messenger RNA (mRNA)IBA 06/2007 - 09/2000
2	Norepinephrine (Noradrenaline)FDA LinkGeneric 06/2007 - 12/2000
2	Nerve Growth Factors (Neurotrophins)IBA 01/2006 - 01/2000
2	NeurotoxinsIBA 01/2006 - 01/2000
2	Nicotine FDA Link 05/2005 - 07/2002
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2005 - 01/2001
1	Levodopa (L Dopa)FDA LinkGeneric 07/2011
1	EndotoxinsIBA 06/2007
1	LipopolysaccharidesIBA 06/2007
1	neuromelaninIBA 01/2006
1	Monoamine Oxidase (MAO)IBA 01/2006
1	XenobioticsIBA 01/2006
1	NF-kappa B (NF-kB)IBA 07/2005
1	dehydroxymethylepoxyquinomicinIBA 07/2005
1	GTP-Binding Proteins (G-Protein)IBA 05/2005
1	Carrier Proteins (Binding Protein)IBA 05/2005
1	Glial Cell Line-Derived Neurotrophic Factor (GDNF)IBA 03/2002
1	AzoxymethaneIBA 12/2001
1	ManganeseIBA 09/2001
1	Serotonin (5 Hydroxytryptamine)IBA 12/2000
1	polyglutamineIBA 09/2000
1	Guanosine Triphosphate (GTP)IBA 09/2000
1	Aromatic-L-Amino-Acid DecarboxylasesIBA 07/2000
1	Tyrosine (L-Tyrosine)FDA Link 05/2000
1	Recombinant ProteinsIBA 05/2000
1	Biomarkers (Surrogate Marker)IBA 03/2000
1	InterleukinsIBA 01/2000
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2000
1	Interleukin-2 (IL2)IBA 01/2000
1	Interleukin-4 (Interleukin 4)IBA 01/2000
1	Interleukin-6 (Interleukin 6)IBA 01/2000
1	Epidermal Growth Factor (EGF)IBA 01/2000
1	Transforming Growth Factor alpha (TGF-alpha)IBA 01/2000
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2000
1	Nerve Growth Factor (NGF)IBA 01/2000
1	isoquinolineIBA 01/2000

Therapy/Procedure

2	Therapeutics 09/2012 - 07/2011